What It Was: A sweet, wispy coo of a love song, performed by Cassie as if she was scribbling mash notes in the back of her 9th-grade english class. Producer Ryan Leslie gave the song the perfect instrumental backing, providing a gentle four-note xylophone-esque hook, being occasionally punctured by heavy, zooming synths. The overall concoction was rich enough that the song became a top five hit in the summer of 2006.

What Happened Next: Typical record label drama, as Bad Boy didn’t seem to know what to do with Cassie after “Me & U,” and a couple poor promotional performances leading up to the release of her self-titled debut album didn’t help. Would-be sophomore album Electro Love never ended up being released.

Where Are They Now?: Cassie’s actually had something of a bounce-back 2012, scoring an international hit with the club-ready “King of Hearts” (though it failed to make inroads Stateside), and appearing as a featured guest on Nicki Minaj’s fine new single “The Boys.” Plus, as the likely main squeeze of hip-hop mogul Diddy, she’ll be staying in the public eye for one reason or another.